Background: Primary non-squamous cell carcinomas of the vulva are rare entities including various tumor types.Among these, primary vulvar intestinal-type adenocarcinoma (vPITA) is extremely rare.Until 3282770208962 2021, less than twenty-five cases have been reported in the literature.Case presentation: We report a case of vPITA in a 63 years old w
The life of a cell is governed by highly dynamical microscopic processes.Two notable examples are the diffusion of membrane receptors and the kinetics of transcription factors governing the rates of gene expression.Different fluorescence imaging techniques have emerged to study molecular dynamics.Among them, fluorescence correlation spectroscopy (F
Targeting cell cycle has become the gold standard for metastatic breast cancer (MBC), being cyclin-dependent kinase inhibitors (CDKIs) cornerstones of its treatment, alongside radiotherapy (RT).To date, no definite evidence regarding safety and efficacy of the combination of CDKIs plus radiotherapy (RT) is currently available.Purpose of this review
Thioredoxin reductases cerini coffee and gifts products are frequently overexpressed in various solid tumors as a protective mechanism against heightened oxidative stress.Inhibitors of this system, such as Auranofin, are effective in eradicating cancer cells.However, the clinical significance of thioredoxin reductase 1 (TrxR1) in lung cancer, as we
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